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Bisoprolol is a beta-blocker that competitively blocks the response of beta receptors, resulting in a decrease in heart rate, myocardial contractility, blood pressure, and myocardial oxygen demand. Bisoprolol also reduces portal hypertension by splanchnic vasoconstriction, which reduces portal blood flow. How to use The dosage of bisoprolol depends on the condition to be treated, and is as follows: Hypertension: 2.5-5 mg daily orally, may be increased to 10 mg, maximum dose 20 mg. Heart failure: 1.25 mg daily orally, may be increased to 10 mg. Here are some tips to follow when using the medication: Take with or without food at the same time of day. It is recommended to take it with food if it causes stomach upset. Monitor your heart rate daily before and after using the medication. This medication may cause fatigue and dizziness due to low blood pressure, so caution should be exercised when performing hazardous activities, such as driving a car or operating machinery. The medication should be discontinued gradually, following instructions from your doctor, as abrupt discontinuation of the medication can worsen heart failure symptoms. This medication may mask some symptoms of low blood sugar, so patients with diabetes should monitor their blood sugar levels carefully while taking this medication. Warnings and precautions Bisoprolol should be used with caution and under the supervision of a physician in the following cases: Patients over 80 years of age. Decreased kidney function. Decreased liver function. Congenital heart disease. Heart valve disease. Patients who have had a heart attack in the past three months. Slowing of electrical conduction between the chambers of the heart (first-degree heart block). A severe form of angina, called Prinzmetal's angina. Peripheral arterial diseases such as Raynaud's syndrome and asthma. Chronic obstructive pulmonary disease. diabetes. Fasting for a long time. History of psoriasis . History of allergies. People who have undergone allergy treatment. Hyperthyroidism. Pregnancy, breastfeeding. Storage Information Store the medicine at room temperature, away from heat and moisture, and out of reach of children. Drug Interactions It is best to inform your doctor or pharmacist about all medications, herbs, vitamins, and nutritional supplements you are taking before starting treatment. It is recommended not to take the following medications at the same time: Bupivacaine . Catecholamine-depleting drugs (eg, reserpine, guanethidine). Antiarrhythmic drugs (eg, disopyramide, flacinide). Some calcium channel blockers (such as diltiazem, verapamil). Cimetidine, digoxin, mefloquine, clonidine because it may increase the risk of excessive blood pressure, especially upon discontinuation. Clonidine . Insulin, as bisoprolol prevents the symptoms of hypoglycemia. Ingredients Bisoprolol
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