Cebo 200 Mg 20 Capsule

Description

CEBO contains the active substance celecoxib. CEBO is used for the relief of signs and symptoms of rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. CEBO belongs to a group of medicinal products called nonsteroidal anti-inflammatory drugs (NSAID), and specifically a sub-group known as (COX-2) inhibitors. Your body makes prostaglandins that may cause pain and inflammation. In conditions such as rheumatoid arthritis and osteoarthritis your body makes more of these. CEBO acts by reducing the production of prostaglandins, thereby reducing the pain and inflammation. How to use Dosage 200 mg capsule, hard: For osteoarthritis the recommended daily dose is 200 mg (1 capsule, hard once a day), increased by your doctor to a maximum of 400 mg (1 capsule, hard twice a day), if needed. For rheumatoid arthritis the initial recommended daily dose is 200 mg (as one 100 mg capsule, hard twice a day), increased by your doctor to a maximum of 400 mg (1 capsule, hard twice a day), if needed. For ankylosing spondylitis the recommended daily dose is 200 mg (1 capsule, hard once a day), increased by your doctor to a maximum of 400 mg (2 capsules, hard once a day or 1 capsule, hard twice a day), if needed. Kidney or liver problems: make sure your doctor knows if you have liver or kidney problems as you may need a lower dose. The elderly, especially those with a weight less than 50 kg: if you are over 65 years of age and especially if you weigh less than 50 kg, your doctor may want to monitor you more closely. Use in children: CEBO is for adults only, it is not for use in children. Warnings and precautions Do not take CEBO Tell your doctor If any of the following are true for you as patients with these conditions should not take CEBO. If you are allergic to celecoxib or any of the other ingredients of this medicine If you have had an allergic reaction to a group of medicines called “sulphonamides” (e.g. some antibiotics used to treat infections) If you currently have an ulcer in your stomach or intestines, or bleeding in your stomach or intestines If you are pregnant. If you can become pregnant during ongoing treatment you should discuss methods of contraception with your doctor If you are breast-feeding If you have severe liver disease If you have severe kidney disease Talk to your doctor, pharmacist or nurse before taking CEBO If you have previously had an ulcer or bleeding in your stomach or intestines. (Do not take CEBO If you currently have an ulcer or bleeding in your stomach or intestine). If you are taking acetylsalicylic acid (even at low dose for heart protective purposes) If you use medicines to reduce blood clotting (e.g. warfarin) If you smoke, have diabetes, raised blood pressure or raised cholesterol If your heart, liver or kidneys are not working well your doctor may want to keep a regular check on you If you have fluid retention (such as swollen ankles and feet) If you are dehydrated, for instance due to sickness, diarrhoea or the use of diuretics (used to treat excess fluid in the body) Side Effects If any of the following happen, stop taking CEBO and tell your doctor immediately: If you have: an allergic reaction such as skin rash, swelling of the face, wheezing or difficulty breathing heart problems such as pain in the chest severe stomach pain or any sign of bleeding in the stomach or intestines, such as passing black or bloodstained stools, or vomiting blood. a skin reaction such as rash, blistering or peeling of the skin liver failure (symptoms may include nausea (feeling sick), diarrhoea, jaundice (your skin or the whites of your eyes look yellow)). Very common: may affect more than 1 in 10 people High blood pressure* Common: may affect up to 1 in 10 people Heart attack* Fluid build up with swollen ankles, legs and/or hands Urinary infections Shortness of breath* Dizziness, difficulty sleeping Vomiting*, stomach ache, diarrhoea, indigestion, wind Rash, itching Muscle stiffness Difficulty swallowing* Worsening of existing allergies Storage Information Do not store above 30o C. Drug Interactions Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines: Dextromethorphan (used to treat coughs) ACE inhibitors or angiotensin II antagonists (used for high blood pressure and heart failure) Diuretics (used to treat excess fluid in the body) Fluconazole and rifampicin (used to treat fungal and bacterial infections) Warfarin or other oral anticoagulants (“blood-thinning” agents that reduce blood clotting) Lithium (used to treat some types of depression) Other medicines to treat depression, sleep disorders, high blood pressure or an irregular heartbeat Neuroleptics (used to treat some mental disorders) Methotrexate (used to treat rheumatoid arthritis, psoriasis and leukaemia) Carbamazepine (used to treat epilepsy/seizures and some forms of pain or depression) Ingredients The active substance is celecoxib. The other ingredients (excipients) are: lactose monohydrate, croscarmellose sodium, povidone K30, sodium lauryl sulphate, magnesium stearate. Capsules 200 mg shells contain gelatin, titanium dioxide (E171).