Coxicel 200 Mg 30 Caps

Description

Coxicel is used in adults for the relief of signs and symptoms of rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. Coxicel belongs to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAID), and specifically a sub-group known as (COX-2) inhibitors. Your body makes prostaglandins that may cause pain and inflammation. In conditions such as rheumatoid arthritis and osteoarthritis your body makes more of these. Coxicel acts by reducing the production of prostaglandins, thereby reducing the pain and inflammation. You should expect your medicine to start working within hours of taking the first dose, but you may not experience a full effect for several days. How to use The recommended dose is: For osteoarthritis the recommended dose is 200 mg each day, increased by your doctor to a maximum of 400 mg, if needed. The dose is usually: one 200 mg capsule once a day; or one 100 mg capsule twice a day. For rheumatoid arthritis the recommended dose is 200 mg each day, increased by your doctor to a maximum of 400 mg, if needed. The dose is usually: one 100 mg capsule twice a day. For ankylosing spondylitis the recommended dose is 200 mg each day, increased by your doctor to a maximum of 400 mg, if needed. The dose is usually: one 200 mg capsule once a day; or one 100 mg capsule twice a day. Warnings and precautions Do not take Coxicel Tell your doctor if any of the following are true for you as patients with these conditions should not take Coxicel. If you are allergic to celecoxib or any of the other ingredients of this medicine If you have had an allergic reaction to a group of medicines called “sulfonamides” (e.g. some antibiotics used to treat infections) If you currently have an ulcer in your stomach or intestines, or bleeding in your stomach or intestines If as a result of taking acetylsalicylic acid or any other anti-inflammatory and painrelieving medicine (NSAID) you have had asthma, nose polyps, severe nose congestion, or an allergic reaction such as an itchy skin rash, swelling of the face, lips, tongue or throat, breathing difficulties or wheezing If you are pregnant. If you can become pregnant during ongoing treatment you should discuss methods of contraception with your doctor If you are breast-feeding If you have severe liver disease If you have severe kidney disease If you have an inflammatory disease of the intestines such as ulcerative colitis or Crohn’s disease Warnings and precautions Talk to your doctor or pharmacist before taking Coxicel: If you have previously had an ulcer or bleeding in your stomach or intestines. (Do not take Coxicel if you currently have an ulcer or bleeding in your stomach or intestine) If you are taking acetylsalicylic acid (even at low dose for heart protective purposes) If you use medicines to reduce blood clotting (e.g. warfarin/warfarin like anticoagulants or novel oral anti-clotting medicines, e.g. apixaban) If you use medicines called corticosteroids (e.g. prednisone) If you are using Coxicel at the same time as other non-acetylsalicylic NSAIDs such as ibuprofen or diclofenac. The use of these medicines together should be avoided If you smoke, have diabetes, raised blood pressure or raised cholesterol If your heart, liver or kidneys are not working well your doctor may want to keep a regular check on you If you have fluid retention (such as swollen ankles and feet) Side Effects If any of the following happen, stop taking Coxicel and tell your doctor immediately: If you have: An allergic reaction such as skin rash, swelling of the face, wheezing or difficulty breathing Heart problems such as pain in the chest Severe stomach pain or any sign of bleeding in the stomach or intestines, such as passing black or bloodstained stools, or vomiting blood A skin reaction such as rash, blistering or peeling of the skin Liver failure (symptoms may include nausea (feeling sick), diarrhoea, jaundice (your skin or the whites of your eyes look yellow)). Very common: may affect more than 1 in 10 people High blood pressure, including worsening of existing high blood pressure * Storage Information Do not store Coxicel above 36o C. Drug Interactions Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines: Dextromethorphan (used to treat coughs) ACE inhibitors, angiotensin II antagonists, beta blockers and diuretics (used for high blood pressure and heart failure) Fluconazole and rifampicin (used to treat fungal and bacterial infections) Warfarin or other warfarin like medicines (“blood-thinning” agents that reduce blood clotting) including newer medicines like apixaban Lithium (used to treat some types of depression) Other medicines to treat depression, sleep disorders, high blood pressure or an irregular heartbeat Neuroleptics (used to treat some mental disorders) Methotrexate (used to treat rheumatoid arthritis, psoriasis and leukaemia) Carbamazepine (used to treat epilepsy/seizures and some forms of pain or depression) Barbiturates (used to treat epilepsy/seizures and some sleep disorders) Ciclosporin and tacrolimus (used for immune system suppression e.g. after transplants) Ingredients The active substance is celecoxib.