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CREVAST belongs to a group of medicines called statins. You have been prescribed CREVAST because: You have a high cholesterol level. This means you are at risk from a heart attack or stroke.You have been advised to take a statin, because changing your diet and taking more exercise were not enough to correct your cholesterol levels. You should continue with your cholestrol-lowering diet and exercise while you are taking CREVAST Or You have other factors that increase your risk of having a heart attack, stroke or related health problems. Heart attack, stroke and other problems can be caused by a disease called atherosclerosis. Atherosclerosis is due to a build up of fatty deposits in your arteris. CREVAST is used to correct the levels of fatty substances in the blood called lipids, the most common of which is cholesterol. There are different types of cholesterol found in the blood – “bad” cholesterol (LDL-C) and “good” cholesterol (HDL-C). CREVAST can reduce the “bad” cholesterol and increase the “good” cholesterol. It works by helping to block your body’s production of “bad” cholesterol. It also improves your body’s ability to remove it from your blood. How to use Recommended dose in adults If you are taking CREVAST for high cholesterol: Starting dose: Your treatment with CREVAST must start with the 5 mg or the 10 mg dose, even if you have taken a higher dose of a different statin before. The choice of your start dose will depend upon: Your cholesterol level. The level of risk you have of experiencing a heart attack or stroke. Whether you have a factor that may make you more sensitive to possible side effects. Please check with your doctor or pharmacist which start dose of CREVAST will best suit you. Your doctor may decide to give you the lowest dose (5 mg) if: You are of Asian origin (Japanese, Chinese, Filipino, Vietnamese, Korean and Indian). You are over 70 years of age. You have moderate kidney problems. You are at risk of muscle aches and pains (myopathy). Increasing the dose and maximum daily dose Your doctor may decide to increase your dose. This is so that you are taking the amount of CREVAST that is right for you. If you started with a 5 mg dose, your doctor may decide to double this to 10 mg then 20 mg and then 40 mg if necessary. If you started on 10 mg, your doctor may decide to double this to 20 mg and then 40 mg if necessary. There will be a gap of four weeks between every dose adjustment. The maximum daily dose of CREVAST is 40 mg. It is only for patients with high cholesterol levels and a high risk of heart attacks or stroke whose cholesterol levels are not lowered enough with 20 mg. If you are taking CREVAST to reduce your risk of having a heart attack, stroke or related health problems: The recommended dose is 20 mg daily. However, your doctor may decide to use a lower dose if you have any of the factors mentioned above. Usual dose in children and adolescents aged 10-17 years The usual start dose is 5mg. your doctor may increase your dose to find the right amount of CREVAST for you. The maximum daily dose of CREVAST is 20 mg. Take your dose once a day. CREVAST 40 mg tablet should not be used by children. Warnings and precautions Do not take CREVAST: If you are allergic to rosuvastatin or any of the other ingredients of this medicine. If you are pregnant or breast-feeding. If you have liver disease. If you have severe kidney problems. If you have repeated or unexplained muscle aches or pains. Warnings and precautions Talk to your doctor or pharmacist before taking CREVAST If you have problems with your kidneys. If you have problems with your liver. If you regularly drink large amounts of alcohol. If your thyroid gland is not working properly. Side Effects Stop taking CREVAST and seek medical help immediately if you have any of the following allergic reactions: Difficulty in breathing, with or without swelling of the face, lips, tongue and/or throat Swelling of the face, lips, tongue and/or throat, which may cause difficulty in swallowing Severe itching of the skin (with raised lumps). Common possible side effects (affects 1 to 10 users in 100): Headache Stomach pain Constipation Feeling sick Muscle pain Feeling weak Dizziness Storage Information Do not store above 30º C. Drug Interactions Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. Tell your doctor if you are taking any of the following: Ciclosporin (used for example, after organ transplants), Warfarin (or any other drug used for thinning the blood), Fibrates (such as gemfibrozil, fenofibrate) or any other medicine used to lower cholesterol (such as ezetimibe), Indigestion remedies (used to neutralise acid in your stomach), Erythromycin (an antibiotic), An oral contraceptive (the pill), Hormone replacement therapy, Lopinavir/ritonavir (used to fight the hiv infection Ingredients The active substance in CREVAST is rosuvastatin.
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