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Daonil 5 mg scored tablets are an oral antidiabetic belonging to a group of medicines called sulfonylureas (medicines that decrease blood sugar levels, or glycemia). It is used to treat non-insulin-dependent diabetes (also called type 2 diabetes, which does not require insulin) when dietarymeasures alone have not been enough to control your blood sugar. How to use The usual dosage is ½ to 3 tablets per day. The tablets are scored, which means that you can break them into two equal halves. Swallow the tablets with about half a glass of water immediately before ameal (oral use). Warnings and precautions Before you take Daonil 5 mg scored tablets, tell your doctor if you or a family member have G6PD (glucose-6-phosphate dehydrogenase) deficiency (hereditary disease of the red blood cells), as there is a risk of hemolysis (destruction of red blood cells) if you take Daonil 5 mg scored tablets. Hypoglycemia: (abnormal decrease in blood sugar levels). The various signs of hypoglycemia include headache, ravenous hunger, nausea, shakiness, sweating, pallor, tiredness, sleepiness, feeling of faintness, dizziness, visual and speech disturbances, behavioral disorders (aggressiveness, depression, confusion), sleep disturbances, impaired concentration, impaired alertness and reactions, and heart problems. During your treatment, you may experience hypoglycemia. If this occurs, you may need to be hospitalized to have your blood sugar levels restored to normal. After an episode of hypoglycemia, your doctor will monitor you carefully for at least 24 hours. Your doctor will explain to you and your family how to avoid episodes of hypoglycemia, how to recognize the first symptoms and how to treat them. The doctor will also describe to you the circumstances in which you might become resistant to this treatment. Side Effects If you experience any of the following symptoms you should contact your doctor or go to the hospital straight away: Very common side effects: Hypoglycemia, which can be severe Common side effects: Skin reactions: rash with spots or patches, Nausea,diarrhea, Weight gain, Storage Information Do not store above 25°C. Drug Interactions Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. Be sure ttell your doctor, in particular, if you are taking any of the following medicines: Medicines that may increase hypoglycemia: Miconazole,fluconazole, Phenylbutazone, Beta-blockers (except esmolol), converting enzyme inhibitors, Clarithromycin,erythromycin, Medicines containing alcohol. Medicines that may cause hyperglycemia (abnormal increase in blood sugar) due treduced efficacy of daonil 5mg scored tablets: Danazol, Chlorpromazine, Glucocorticosteroids(excepthydrocortisone), Salbutamol,terbutaline, Ritodrine. Other possible interactions: Bosentan: risk of increase in certain liver enzymes, Somatostatin analogues: risk of hyperglycemia or hypoglycemia, Colesevelam: daonil 5 mg scored tablets should be taken at least 4 hours before colesevelam. Ingredients The active substance is: Glibenclamide The other ingredients are: lactosemonohydrate, maize starch, pregelatinized maize starch, talc, colloidal anhydrous silica,magnesium stearate.
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