Diacerein 50 Mg 30 Hard Gelatin Capsules

Description

Diacerein is a slow-acting drug belonging to the anthraquinone family, primarily used to treat osteoarthritis. It works by inhibiting the activity of the protein interleukin-1, which contributes to inflammation and cartilage deterioration. It also inhibits the release of cytokines such as interferon-1 and stimulates the formation of collagen and glycosaminoglycans, making it anti-inflammatory and cartilage-protective. How to use Usually 50 mg once or twice daily, preferably taken with food. Long-term use is required for optimal benefits as effects develop gradually. Warnings and precautions Contraindications Diacerein should not be used without consulting a specialist doctor in the following cases: Allergy to the components of the drug. Patients over 65 years of age. During pregnancy or breastfeeding. Patients with liver disease or a history of liver problems. Children under 15 years of age. Inflammatory bowel diseases, such as Crohn's disease or ulcerative colitis. Undiagnosed abdominal pain. Precautions when using Stop using the medicine and consult a doctor if severe diarrhea occurs. Consult a doctor if symptoms such as itching or jaundice occur, as these may be signs of liver problems. Use with caution in the following cases: Gastrointestinal diseases or kidney failure. Elevated liver enzyme levels. Elderly patients over 65 years of age. Side Effects Common side effects may include: Skin related: rash, eczema, itching. Digestive system: abdominal pain, diarrhea (acute or chronic), pigmentation of the rectal mucosa. Liver: elevated liver enzymes, liver disorders, jaundice. Other: Urine turns dark. Storage Information Store at a temperature not exceeding 30°C. Store in a dry place away from moisture and direct sunlight. Do not refrigerate or freeze. Drug Interactions You should inform your doctor or pharmacist about any medications, herbs, vitamins, or nutritional supplements you are taking. Diacerein may interact with: Warfarin Aceclofenac Antacids (such as aluminum hydroxide) – preferably separated from Diaserine by at least two hours. Cardiac glycosides Diuretics (such as chlorothiazide) Ingredients Diacerein