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Disprin 81 tablets contain acetylsalicylic acid, which in low doses belong to a group of medicines called anti-platelet agents Platelets are tiny cells in the blood that cause the blood to clot and are involved in thrombosis. When a blood clot occurs in an artery it stops the blood flowing and cuts off the oxygen supply. When this happens in the heart it can cause a heart attack or angina; in the brain it can cause a stroke Disprin 81 tablets are taken to reduce the risk of blood clots forming and thereby prevent further Heart attacks Strokes Cardiovascular problems in patients who suffer from stable or unstable-angina (a type of chest pain) Disprin 81 tablets are also used in the treatment of acute heart attack and to prevent the formation of blood clots after certain types of heart surgery in order to widen or to unblock the blood vessels. This medicinal product is not recommended for emergencies. It can only be used as a preventive treatment How to use Adults Prevention of heart attacks: The recommended dose is 75-160mg once daily- Prevention of strokes: The recommended dose is 75-325mg once daily- Prevention of cardiovascular problems in patients who suffer from stable or unstable angina (a type of chest pain): The recommended dose is 75-160mg once daily: Prevention formation of blood clots after certain types of heart surgery The recommended dose is 75-160mg once daily: Acute heart attack The recommended dose is 150-450mg, taken as soon as possible after onset of symptom- Elderly As for adults. In general, acetylsalicylic acids should be used with caution in elderly patients who are more prone to adverse events. Treatment should be reviewed at regular intervals Children Acetylsalicylic acid should not be administered to children and adolescents younger than 16 years, unless prescribed by a doctor, see section “Take special care with Disprin 81 tablets Method of administration For oral use. The tablets should be swallowed whole with sufficient fluid 1/2 glass of water. The tablets have a coating which prevents irritant effects on the gut, and should therefore not be crushed, broken or chewed Warnings and precautions Before you take disprin 81 tablets tell your doctor if you Have trouble with your kidneys, liver or heart Have or have ever had problems with your stomach or small intestine Have high blood pressure Are asthmatic, have hay fever, nasal polyps or other chronic respiratory diseases; acetylsalicylic acid may induce an asthma attack- Have ever had gout- Have heavy menstrual periods Side Effects If you notice any of the following serious side effects, stop taking Disprin 81 tablets and contact a doctor immediately: Sudden wheezing, swelling of your lips, face or body, rash, fainting or difficulties swallowing (severe allergic reaction- Reddening of the skin with blisters or peeling and may be associated with a high fever and joint pains.This could by erythema multiforme, Stevens-Johnson syndrome or Lyell’s syndrome- Unusual bleeding, such as coughing up blood, blood in your vomit or urine, or black stools- Common side effects (may affect up to 1 in 10 people) Indigestion Increased tendency for bleeding- Storage Information Store below 30°C, in a dry place Drug Interactions The effect of treatment may be influenced if acetylsalicylic acid is taken at the same time as some other medicines for Thinning of the blood/prevention of clots (e.g. warfarin, heparin, clopidogrel) Rejection of organ after transplantation (cyclosporine, tacrolimus) High blood pressure (e.g. diuretics and ACE-inhibitors- Regulation of the heart beat (digoxin) Manic-depressive illness (lithium) Pain and inflammation, e.g. NSAIDs such as ibuprofen, or steroids Gout (e.g. probenecid) Epilepsy (valproate, phenytoin) Glaucoma (acetazolamide) Iron deficiency anemia (Iron Salts) Peptic ulcer & reflux (Carbonates) Heartburn (Antacid “Alkyl hydroxide”) Ingredients The active substance is acetylsalicylic acid Specifications Orange color, circular, biconvex, enteric coated tablets with “RP” on one side and “91” embossed on other side of the tablet
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