ETOXIB 60MG 28TAB

Description

Etoxib contains the active substance Etoxib. Etoxib is one of a group of medicines called selective COX-2 inhibitors. These belong to a family of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). Etoxib helps to reduce the pain and swelling (inflammation) in the joints and muscles of people 16 years of age and older with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and gout. Etoxib is also used for the short term treatment of moderate pain after dental surgery in people 16 years of age and older. How to use The recommended dose is: Osteoarthritis The recommended dose is 30 mg once a day, increase to a maximum of 60 mg once a day if needed. Rheumatoid arthritis The recommended dose is 60 mg once a day, increased to a maximum of 90 mg once a day if needed. Ankylosing spondylitis The recommended dose is 60 mg once a day, increased to a maximum of 90 mg once a day if needed. Acute pain conditions Etoxib should be used only for the acute painful period. Gout The recommended dose is 120 mg once a day which should only be used for the acute painful period, limited to a maximum of 8 days treatment. Postoperative dental surgery pain the recommended dose is 90 mg once daily, limited to a maximum of 3 days treatment. People with liver problems If you have mild liver disease, you should not take more than 60 mg a day. If you have moderate liver disease, you should not take more than 30 mg a day. Warnings and precautions Do not take Etoxib: If you are allergic (hypersensitive) to Etoxib or any of the other ingredients of this medicine. If you are allergic to non-steroidal anti-inflammatory drugs (NSAIDs), including aspirin and COX-2 inhibitors If you have a current stomach ulcer or bleeding in your stomach or intestines If you have serious liver disease If you have serious kidney disease If you are or could be pregnant or are breast-feeding If you are under 16 years of age If you have inflammatory bowel disease, such as Crohn’s Disease, Ulcerative Colitis, or Colitis If you have high blood pressure that has not been controlled by treatment (check with your doctor or nurse if you are not sure whether your blood pressure is adequately controlled). If your doctor has diagnosed heart problems including heart failure (moderate or severe types), angina (chest pain). WARNINGS AND PRECAUTIONS: Talk to your doctor or pharmacist before taking Etoxib if: You have a history of stomach bleeding or ulcers. You are dehydrated, for example by a prolonged bout of vomiting or diarrhoea. You have swelling due to fluid retention. You have a history of heart failure, or any other form of heart disease. You have a history of high blood pressure. Etoxib can increase blood pressure in some people, especially in high doses, and your doctor will want to check your blood pressure from time to time. You have any history of liver or kidney disease. You are being treated for an infection. Etoxib can mask or hide a fever, which is a sign of infection. You have diabetes, high cholesterol, or are a smoker. These can increase your risk of heart disease. You are a woman trying to become pregnant. You are over 65 years of age. Side Effects If you develop any of these signs you should stop Etoxib and talk to your doctor immediately: Shortness of breath, chest pains, or ankle swelling appear or if they get worse Yellowing of the skin and eyes (jaundice) – these are signs of liver problems Severe or continual stomach pain or your stools become black An allergic reaction- which can include skin problems such as ulcers or blistering, or swelling of the face, lips, tongue, or throat which may cause difficulty in breathing The following side effects can occur during treatment with Etoxib : Very Common: Stomach pain Storage Information Store below 30ºC. Protect from light and moisture Drug Interactions In particular if you are taking any of the following medicines, your doctor may want to monitor you to check that your medicines are working properly, once you start taking Etoxib. Medicines that thin your blood (anticoagulants), such as warfarin Rifampicin (an antibiotic) Methotrexate (a drug used for suppressing the immune system, and often used in rheumatoid arthritis). Ciclosporin or tacrolimus (drugs used for suppressing the immune system) Lithium (a medicine used to treat some types of depression) Medicines used to help control high blood pressure and heart failure called ACE inhibitors and angiotensin receptor blockers, examples include enalapril and ramipril, and losartan and valsartan diuretics (water tablets). Digoxin (a medicine for heart failure and irregular heart rhythm) Minoxidil (a drug used to treat high blood pressure) Salbutamol tablets or oral solution (a medicine for asthma) Birth control pills (the combination may increase your risk of side effects) Hormone replacement therapy (the combination may increase your risk of side effects) Aspirin, the risk of stomach ulcers is greater if you take Etoxib with aspirin. Ingredients The active substance is Etoricoxib. The other ingredients are: Calcium hydrogen phosphate Anhydrous, Microcrystalline Cellulose, Croscarmellose sodium, Povidone K-25, Magnesium stearate, Opadry II Green 32K210019, Opadry II Green 32K210011, Opadry II White 32K580000 & Purified water.