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Evoka contains an active substance called ‘dapoxetine’. This belongs to a group of medicines called ‘selective serotonin reuptake inhibitors’ (SSRIs). Evoka may also be known as a ‘urological’ medicine. Evoka increases the time it takes to ejaculate and can improve the control over the ejaculation. This may reduce the frustration or worry about fast ejaculation. Evoka is used to treat premature ejaculation in adult men aged 18 to 64 years. Premature ejaculation is when a man ejaculates with little sexual stimulation and before the man wants. This can cause problems for the man and may cause problems in sexual relationships. How to use The recommended dose is 30 mg. Your doctor may increase the dose to 60 mg. Only take the medicine 1 to 3 hours before sexual activity is anticipated. Do not take this medicine more than once every 24 hours or every day. Swallow the tablets whole to avoid a bitter taste, with at least one full glass of water. This may help lower your chance of fainting This medicine can be taken with or without food. This medicine should not be used by men under 18 or over 65 years of age. Discuss your treatment with your doctor after the first 4 weeks or after 6 doses to see whether you should continue treatment. If treatment is continued, you should see your doctor again to discuss this at least every six months. Warnings and precautions Do not take Evoka if: You are allergic to dapoxetine or any of the other ingredients of this medicine You have heart problems, such as heart failure or problems with the heart rhythm You have a history of fainting You have ever had mania (symptoms include feeling over-excited, irritable or not being able to think clearly) or severe depression You have moderate or severe liver problems. Warnings and precautions Talk to your doctor, pharmacist or nurse before taking Evoka if: You have not been diagnosed with premature ejaculation You also have another sexual problem, such as erectile dysfunction You have a history of dizziness from low blood pressure You use recreational drugs such as ecstasy, LSD, narcotics or benzodiazepines You drink alcohol You have ever had a mental health problem such as depression, mania (symptoms include feeling over-excited, irritable or not being able to think clearly), bipolar disorder (symptoms include serious mood swings between mania and depression) or schizophrenia (a psychiatric disease) You have epilepsy You have a history of bleeding or blood clotting problems You have kidney problems You have, or are at risk of, high pressure in the eye (glaucoma). Side Effects Stop taking Evoka and see your doctor straight away if: You have fits (seizures) You faint or feel light headed when you stand up You notice any changes in your mood You have any thoughts of suicide or harming yourself. Very common side effects (may affect more than 1 in 10 men): Feeling dizzy Headache Feeling sick. Common side effects (may affect up to 1 in 10 men): Feeling irritable, anxious, agitated or restless Feeling numb or having ‘pins and needles’ Difficulty getting or keeping an erection Sweating more than normal or flushing Diarrhoea, constipation or having wind Stomach pain, bloating or being sick Problems sleeping or strange dreams Feeling tired or sleepy, yawning Blocked nose (nasal congestion) A rise in blood pressure Difficulty concentrating Shaking or trembling Lower interest in sex Ringing in the ears Blurred vision Indigestion Dry mouth. Storage Information Store below 30°C. Drug Interactions Do not take Evoka at the same time as any of the following medicines: Medicines for depression called ‘monoamine oxidase inhibitors’ (MAOIs) Thioridazine used for schizophrenia Other medicines for depression Lithium - a medicine for bipolar disorder Linezolid - an antibiotic used to treat infections Tryptophan - a medicine to help you sleep St John’s wort - a herbal medicine Tramadol - used to treat serious pain Medicines used to treat migraines. Ingredients The active substance is dapoxetine.