Incresync 25/15 Mg 28 Tablets

Description

Incresync contains two different medicines called alogliptin and pioglitazone in one tablet: Alogliptin belongs to a group of medicines called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). Alogliptin works to increase the levels of insulin in the body after a meal and decrease the amount of sugar in the body. Pioglitazone belongs to a group of medicines called thiazolidinediones. It helps your body make better use of the insulin it produces. Both of these groups of medicines are “oral anti-diabetics”. Incresync is used to lower blood sugar levels in adults with type 2 diabetes. Type 2 diabetes is also called non-insulin-dependent diabetes mellitus or NIDDM. Incresync is taken when your blood sugar cannot be adequately controlled by diet, exercise and other oral anti-diabetic medicines such as pioglitazone; or pioglitazone and metformin taken together. Your doctor will check whether Incresync is working 3 to 6 months after you start taking it. How to use Your doctor will tell you how much Incresync you need to take and if you need to change the amount of other medicines you take. The maximum recommended daily dose is 25 mg alogliptin and 45 mg pioglitazone. Incresync should be taken once daily. Swallow your tablet(s) whole with water. You can take this medicine with or without food. If you have kidney problems your doctor may prescribe you a reduced dose. If you are following a diabetic diet, you should continue with this while you are taking Incresync. Your weight should be checked at regular intervals; if your weight increases, tell your doctor. Warnings and precautions Do not take Incresync If you are allergic to alogliptin, pioglitazone or any of the other ingredients of this medicine If you have had a serious allergic reaction to any other similar medicines that you take to control your blood sugar. Symptoms of a serious allergic reaction may include; rash, raised red patches on your skin (hives), swelling of the face, lips, tongue, and throat that may cause difficulty in breathing or swallowing. Additional symptoms may include general itching and feeling of heat especially affecting the scalp, mouth, throat, palms of hands and soles of feet (Stevens-Johnson syndrome). If you have heart failure or have had heart failure in the past. If you have liver disease. If you have diabetic ketoacidosis (a serious complication of poorly controlled diabetes). Warnings and Precautions Talk to your doctor or pharmacist before taking Incresync: If you have type 1 diabetes (your body does not produce insulin). If you are taking an anti-diabetic medicine known as sulphonylurea (e.g. glipizide, tolbutamide, glibenclamide) or insulin. If you suffer from heart disease or fluid retention. If you take anti-inflammatory medicines which can also cause fluid retention and swelling, you must also tell your doctor. If you are elderly and are taking insulin, because you may have an increased risk of heart problems. If you have a problem with your liver or kidneys. Before you start taking this medicine you will have a blood sample taken to check your liver and kidney function. This check may be repeated at intervals. In case of kidney disease, your doctor may reduce the dose of Incresync. If you have a special type of diabetic eye disease called macular oedema (swelling of the back of the eye). If you have cysts on your ovaries (polycystic ovarian syndrome). There may be an increased possibility of becoming pregnant because you may ovulate again when you take Incresync. If you have or have had a disease of the pancreas. Side Effects STOP taking Incresync and contact a doctor immediately if you notice any of the following serious side effects: Common (may affect up to 1 in 10 people): Sudden and severe bone pain or immobility (particularly in women). You should also discuss with your doctor if you experience the following side effects: Common: Symptoms of low blood sugar (hypoglycaemia) may occur when Incresync is taken in combination with insulin or sulphonylureas (e.g. glipizide, tolbutamide, glibenclamide). Symptoms may include: trembling, sweating, anxiety, blurred vision, tingling lips, paleness, mood change or feeling confused. Your blood sugar could fall below the normal level, but can be increased again by taking sugar. It is recommended that you carry some sugar lumps, sweets, biscuits or sugary fruit juice. Cold or flu-like symptoms such as sore throat, stuffy or blocked nose Inflammation of the sinuses (sinusitis) Itchy skin Headache Stomach ache Diarrhoea Indigestion, heartburn Feeling sick Muscle pain Feeling numb in any part of your body Blurred or distorted vision Weight gain Swollen or puffy hands or feet Rash Storage Information Do not store above 30°C. Store in the original package in order to protect from moisture. Drug Interactions In particular tell your doctor or pharmacist if you are taking any of the following: Gemfibrozil (used to lower cholesterol) Rifampicin (used to treat tuberculosis and other infections) Ingredients The active substances are alogliptin benzoate and pioglitazone hydrochloride.