Janumet 50/1000 mg 56 Tablets

Description

Janumet contains two different medicines: sitagliptin and metformin. Sitagliptin belongs to a class of medications called DPP-4 inhibitors (dipeptidyl peptidase IV inhibitors). Metformin belongs to a class of medications called pegionides. They work together to control blood sugar levels in adults with type 2 diabetes. This medicine helps improve insulin levels after eating and reduces the amount of sugar the body produces. This medication helps lower blood sugar levels in conjunction with diet and exercise. This medication may be used alone or with certain other diabetes medications such as (insulin, sulfonylureas, glitazones). How to use This medicine should be taken: One tablet, twice daily by mouth. With meals to reduce the chance of stomach upset. Your doctor may need to increase your dose to control your blood sugar level. If you have poor kidney function, your doctor may prescribe a lower dose. You should continue your diet while being treated with this medicine, making sure that carbohydrates are distributed evenly throughout the day. Warnings and precautions Cases of inflammation of the pancreas (pancreatitis) have been reported in patients receiving this medicine. If you experience skin blistering, it may be a sign of a condition called bullous pemphigoid. Your doctor may ask you to stop this medication. Risk of lactic acidosis. Talk to your doctor or pharmacist before taking: If you have or have ever had a disease of the pancreas (such as pancreatitis) If you have gallstones, alcoholism or very high levels of triglycerides (a type of fat) in your blood. If you have type 1 diabetes. This is sometimes called insulin-dependent diabetes. If you have or have had an allergic reaction to sitagliptin, metformin If you are taking a sulfonylurea or insulin and diabetes medications, together Side Effects Stop taking Janumet and see your doctor right away if you notice any of the following serious symptoms: Severe, persistent abdominal (stomach) pain that may extend to the back area with or without nausea or feeling sick (vomiting), which may be symptoms of pancreatitis. In very rare cases, Janumet may cause a serious condition called lactic acidosis (affects up to 1 in 10,000 people). If this happens, stop taking Janumet and see your doctor or nearest hospital immediately, as lactic acidosis can lead to coma. If you have a serious allergic reaction (frequency not known), including rash, hives, skin peeling, or swelling of the face, lips, tongue, or throat that may cause difficulty breathing or swallowing, stop taking this medicine and call your doctor right away. Your doctor may prescribe an allergy medicine and another diabetes medicine. Storage Information Store at a temperature below 30°C. Drug Interactions Medicines taken orally, by inhalation or injection, which are used to treat diseases that involve inflammation such as asthma and arthritis (corticosteroids). Medications that increase urine production (diuretics). Medications used to treat pain and inflammation (anti-inflammatory drugs and COX-2 inhibitors, such as ibuprofen and celecoxib) Certain medications to treat high blood pressure (ACE inhibitors and angiotensin II receptor blockers). Certain medications for the treatment of bronchial asthma (beta-sympathomimetics). Iodine contrast agent or medications containing alcohol. Certain medications to treat stomach disorders, such as cimetadine. Ranolazine is a medication used to treat angina. Dolutegravir is a medicine used to treat HIV infection. Vandetanib is a medicine used to treat a certain type of thyroid cancer (medullary thyroid cancer). Dagoxin (to treat irregular heartbeats and other heart disorders). Your blood digoxin level may need to be checked if you take it with Janumet. Ingredients Sitagliptin, metformin, microcrystalline cellulose (E460), povidone (K 29/32)(E1201), sodium lauryl sulphate, and sodium stearyl fumarate, polyvinyl alcohol, macrogol (3350), talc (E553b), titanium dioxide (E171), red iron oxide (E172), black iron oxide (E172). Specifications Janumet 50 mg/1000 mg film-coated tablets are capsule-shaped, red in colour and engraved with “577” on one side.