Lunia 40/10 Mg 28 Tab

Description

Lunia contains the active substances ezetimibe and simvastatin. Lunia is a medicine used to lower levels of total cholesterol, “bad” cholesterol (LDL cholesterol), and fatty substances called triglycerides in the blood. In addition, Lunia raises levels of “good” cholesterol (HDL cholesterol). Lunia works to reduce your cholesterol in two ways. The active ingredient ezetimibe reduces the cholesterol absorbed in your digestive tract. The active ingredient simvastatin belonging to the class of “statins” inhibits the production of the cholesterol your body makes by itself. How to use The tablets are not scored and should not be divided. Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure. Before starting Lunia, you should be on a diet to lower your cholesterol. You should keep on this cholesterol-lowering diet while taking Lunia. Adults: The dose is 1 tablet Lunia by mouth once a day. Use in adolescents (10 to 17 years of age): The dose is 1 tablet Lunia by mouth once a day (a maximum dose of 10 mg/40 mg once daily must not be exceeded). The Lunia 10 mg/80 mg dose is only recommended for adult patients with very high cholesterol levels and at high risk of heart disease problems who have not reached their cholesterol goal on lower doses. Take Lunia in the evening. You can take it with or without food. If your doctor has prescribed Lunia along with another medicine for lowering cholesterol containing the active ingredient cholestyramine or any other bile acid sequestrant, you should take Lunia at least 2 hours before or 4 hours after taking the bile acid sequestrant. Warnings and precautions Do not take Lunia If you are allergic (hypersensitive) to ezetimibe, simvastatin, or any of the other ingredients of this medicine (listed in Section 6: Further information). If you currently have liver problems. If you are pregnant or breast-feeding. If you are taking or have taken, in the last 7 days, a medicine called fusidic acid (a medicine for bacterial infection) orally or by injection. The combination of fusidic acid and Lunia can lead to serious muscle problems (rhabdomyolysis). Do not take more than 10/40 mg Lunia if you are taking lomitapide (used to treat a serious and rare genetic cholesterol condition). Warnings and precautions Tell your doctor: About all your medical conditions including allergies, If you drink large amounts of alcohol or have ever had liver disease. Lunia may not be right for you, If you are due to have an operation. You may need to stop taking Lunia tablets for a short time, If you are Asian, because a different dose may be applicable to you. Side Effects Like all medicines, this medicine can cause side effects, although not everybody gets them. These effects are normally mild to moderate in nature. Common (may affect more than or equal to 1 in 100 and less than 1 in 10 people) muscle aches, elevations in laboratory blood tests of liver (transaminases) and/or muscle (CK) function. Uncommon (may affect more than or equal to 1 in 1000 and less than 1 in 100 people) elevations in blood tests of liver function; elevations in blood uric acid; elevations in the time it takes for blood to clot; protein in urine; weight decreased, dizziness; headache; tingling sensation, abdominal pain; indigestion; flatulence; nausea; vomiting; abdominal bloating; diarrhoea; dry mouth; heartburn, rash; itching; hives, joint pain; muscle pain, tenderness, weakness or spasms; neck pain; pain in arms and legs; back pain, unusual tiredness or weakness; feeling tired; chest pain; swelling, especially in the hands and feet, sleep disorder; trouble sleeping. Storage Information Store in the original package in order to protect from moisture and light Do not store above 30°C. Drug Interactions If you need to take oral fusidic acid to treat a bacterial infection you will need to temporarily stop using this medicine. Your doctor will tell you when it is safe to restart Lunia. Taking Lunia with fusidic acid may rarely lead to muscle weakness, tenderness or pain (rhabdomyolysis). ciclosporin (often used in organ transplant patients), danazol (a man-made hormone used to treat endometriosis, a condition in which the lining of the uterus grows outside the uterus), medicines with an active ingredient like itraconazole, ketoconazole, fluconazole, posaconazole, or voriconazole (used to treat fungal infections), fibrates with active ingredients like gemfibrozil and bezafibrate (used to lower cholesterol), erythromycin, clarithromycin, or telithromycin (used to treat bacterial infections), HIV protease inhibitors such as indinavir, nelfinavir, ritonavir, and saquinavir (used to treat AIDS), Hepatitis C antiviral agents such as boceprevir, telaprevir, elbasvir, or grazoprevir (used to treat hepatitis C virus infection), nefazodone (used to treat depression), medicines with the active ingredient cobicistat, amiodarone (used to treat an irregular heartbeat), verapamil, diltiazem, or amlodipine (used to treat high blood pressure, chest pain associated with heart disease, or other heart conditions), lomitapide (used to treat a serious and rare genetic cholesterol condition), Ingredients The active substance is ezetimibe and simvastatin.