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Nexium contains a medicine called esomeprazole. This belongs to a group of medicines called 'proton pump inhibitors'. They work by reducing the amount of acid that your stomach produces. Nexium is used to treat the following conditions: Adults Gastroesophageal reflux disease' (GERD). This is where acid from the stomach escapes into the gullet (the tube which connects your throat to your stomach) causing pain, inflammation and heartburn. Ulcers in the stomach or upper part of the gut (intestine) that are infected with bacteria called 'Helicobacter pylori'. If you have this condition, your doctor may also prescribe antibiotics to treat the infection and allow the ulcer to heal. Stomach ulcers caused by medicines called NSAIDs (Non-Steroidal Anti-Inflammatory Drugs). Nexium can also be used to stop stomach ulcers from forming if you are taking NSAIDs. Too much acid in the stomach caused by a growth in the pancreas (Zollinger-Ellison syndrome). Prolonged treatment after prevention of rebleeding of ulcers with intravenous Nexium. Adolescents aged 12 years and above 'Gastroesophageal reflux disease' (GERD). This is where acid from the stomach escapes into the gullet (the tube which connects your throat to your stomach) causing pain, inflammation and heartburn. Ulcers in the stomach or upper part of the gut (intestine) that are infected with bacteria called 'Helicobacter pylori'. If you have this condition, your doctor may also prescribe antibiotics to treat the infection and allow the ulcer to heal. How to use The recommended dose is one tablet per day. Do not take more than this recommended dose of one capsule (20 mg) per day, even if you do not feel better right away. You may need to take the capsules for two or three days in a row before your reflux symptoms (for example, heartburn and acid reflux) improve. The duration of treatment is up to 14 days. When your reflux symptoms have completely disappeared, you should stop taking this medicine. If your reflux symptoms get worse or do not improve after taking this medicine for 14 days in a row, you should consult your doctor. If you have persistent or long-lasting symptoms that occur repeatedly even after treatment with this medicine, you should contact your doctor. Taking this medicine You can take the capsule at any time of the day, either with food or on an empty stomach. Swallow the capsule whole with half a glass of water. Do not chew, crush or open the capsule. This is because the capsule contains coated globules, which prevent the medicine from being broken down by the acid in your stomach. Warnings and precautions Talk to your doctor or pharmacist before taking Nexium: If you have severe liver problems. If you have severe kidney problems. If you have ever had a skin reaction after treatment with a medicine similar to Nexium that reduces stomach acid. If you are due to have a specific blood test (Chromogranin A). Side Effects If you experience any of the following symptoms you should contact your doctor or go to the hospital straight away: Common (may affect up to 1 in 10 people) Headache. Effects on your stomach or gut: diarrhoea, stomach pain, constipation, wind (flatulence). Feeling sick (nausea) or being sick (vomiting). Benign polyps in the stomach. Storage Information Do not store above 30°C. Keep this medicine in the original container (blister) in order to protect from moisture. Drug Interactions Tell your doctor or pharmacist if you are taking any of the following medicines: Atazanavir (used to treat HIV infection). Clopidogrel (used to prevent blood clots). Ketoconazole, itraconazole or voriconazole (used to treat infections caused by a fungus). Erlotinib (used to treat cancer). Diazepam (used to treat anxiety or relax muscles). Citalopram, imipramine or clomipramine (used to treat depression). Phenytoin (used in epilepsy). Warfarin or coumarin (medicines called anticoagulants that are used to thin your blood). Ingredients The active substance is esomeprazole. Specifications Nexium 40 mg gastro-resistant tablets are pink in colour and imprinted A/EI on one side and 40 mg on the other side.
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