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Each tablet of Pantoloc®40 contains Pantoprazole sodium sesquihydrate equivalent to Pantoprazole 40mg. Pantoloc®40 Tablets is indicated in duodenal ulcer, Gastric ulcer, Moderate and severe forms gastro esophageal Reflux disease (GERD). Gastroesophageal reflux disease (GERD) and moderate to severe esophageal reflux disease (GERD). Pantoloc® 40 mg tablets is a proton pump inhibitor (PPI), a medication that reduces the amount of acid secreted in the stomach. It is used to treat acid-related disorders affecting the stomach and intestines. How to use Unless otherwise prescribed, the following oral doses are recommended: Duodenal and gastric ulcers and reflux esophagitis: The recommended dose is one tablet daily. In individual cases, up to 2 Pantoloc®40 tablets daily can be administrated to patients with GERD, gastric or duodenal ulcers, particularly, if they have not responded to other drugs. In elderly patients with impaired renal functions, the daily dose should not exceed one Pantoloc®40 tablets. In case of severely reduced liver functions, the dosage should be reduced to one Pantoloc®40 tablets every other day. Pantoloc®40 tablets should not be chewed or crushed and should be taken with liquid either before or during breakfast. Duodenal ulcers generally heal within 2 weeks. Gastric ulcer and GERD usually require 4 weeks of treatment. In individual cases, treatment can be prolonged to 4 weeks (duodenal ulcers) or 8 weeks (gastric ulcers and GERD). Duration of therapy is 8 weeks and may be extended for an additional 8 weeks if esophageal healing is incomplete. Warnings and precautions Do not take Pantoloc®40 Tablets and tell your doctor or pharmacist if you have: Known hypersensitivity to any of its components. Take special care with Pantoloc®40 Tablets In patients with severe hepatic dysfunction, liver enzymes should be checked regularly during treatment with Pantoprazole. In case of increase in liver enzymes, Pantoprazole should be discontinued. Side Effects Pantoprazole can occasionally lead to headache or diarrhea. There were rare reports of nausea, upper abdominal pain, flatulence, skin rash, pruritis or dizziness. Edema, fever, the onset of depression and disturbances in vision (blurred vision) were reported in individual cases. Storage Information Store at temperature not exceeding 30oC. Drug Interactions Pantoloc®40 may reduce the absorption of drugs whose bio-availability is pH-dependent e.g:ketoconazole, ampicillin and iron salt. Pantoprazole is metabolized in the liver via cytochrome P450 enzyme system. Interaction with other drugs which are metabolized using the same enzyme system cannot be excluded. Ingredients The active substance is Pantoprazole as (sodium sesquihydrate). Specifications Pantoloc® 40 are pale yellow colored circular, biconvex enteric coated tablets.
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