Prasido 90 Mg 56 Tab

Description

Prasido® contains an active substance called ticagrelor. This belongs to a group of medicines called antiplatelet medicines. Prasido® in combination with acetylsalicylic acid (another antiplatelet agent) is to be used in adults only. You have been given this medicine because you have had: A heart attack, or Unstable angina (angina or chest pain that is not well controlled). It reduces the chances of you having another heart attack, stroke or dying from a disease related to your heart or blood vessels. Prasido® affects cells called ‘platelets’ (also called thrombocytes). These very small blood cells help stop bleeding by clumping together to plug tiny holes in blood vessels that are cut or damaged. However, platelets can also form clots inside diseased blood vessels in the heart and brain. This can be very dangerous because: The clot can cut off the blood supply completely; this can cause a heart attack (myocardial infarction) or stroke, or The clot can partly block the blood vessels to the heart; this reduces the blood flow to the heart and can cause chest pain which comes and goes (called ‘unstable angina’). Prasido® helps stop the clumping of platelets. This reduces the chance of a blood clot forming that can reduce blood flow How to use How much to take The starting dose is two tablets at the same time (loading dose of 180 mg). This dose will usually be given to you in the hospital. After this starting dose, the usual dose is one tablet of 90 mg twice a day for up to 12 months unless your doctor tells you differently. Take this medicine around the same time every day (for example, one tablet in the morning and one in the evening). Taking Prasido® with other medicines for blood clotting Your doctor will usually also tell you to take acetylsalicylic acid. This is a substance present in many medicines used to prevent blood clotting. Your doctor will tell you how much to take (usually between 75-150 mg daily). How to take Prasido® You can take the tablet with or without food. Warnings and precautions Do not take Prasido®: If you are allergic to ticagrelor or any of the other ingredients of this medicine. If you are bleeding now. If you have had a stroke caused by bleeding in the brain. If you have severe liver disease. If you are taking any of the following medicines: Ketoconazole (used to treat fungal infections). Clarithromycin (used to treat bacterial infections). Nefazodone (an antidepressant). Ritonavir and atazanavir (used to treat HIV infection and AIDS). Warnings and precautions Talk to your doctor or pharmacist before taking Prasido®: If you have an increased risk of bleeding because of: A recent serious injury Recent surgery (including dental work, ask your dentist about this) You have a condition that affects blood clotting Recent bleeding from your stomach or gut (such as a stomach ulcer or colon ‘polyps’) If you are due to have surgery (including dental work) at any time while taking Prasido®. This is because of the increased risk of bleeding. Your doctor may want you to stop taking this medicine 7 days prior to surgery. If your heart rate is abnormally low (usually lower than 60 beats per minute) and you do not already have in place a device that paces your heart (pacemaker). If you have asthma or other lung problems or breathing difficulties. If you have had any problems with your liver or have previously had any disease which may have affected your liver. If you have had a blood test that showed more than the usual amount of uric acid Side Effects Prasido® affects blood clotting, so most side effects are related to bleeding. Bleeding may occur in any part of the body. Some bleeding is common (like bruising and nosebleeds). Severe bleeding is uncommon, but can be life threatening. Other possible side effects Very common (may affect more than 1 in 10 people): High level of uric acid in your blood (as seen in tests). Bleeding caused by blood disorders. Common (may affect up to 1 in 10 people): Bruising. Headache. Feeling dizzy or like the room is spinning. Diarrhea or indigestion. Feeling sick (nausea). Constipation. Rash. Itching. Storage Information Store below 30°C. Drug Interactions Tell your doctor or pharmacist if you are taking any of the following medicines: More than 40 mg daily of either simvastatin or lovastatin (medicines used to treat high cholesterol). Rifampicin (an antibiotic). Phenytoin, carbamazepine and phenobarbital (used to control seizures). Digoxin (used to treat heart failure). Cyclosporine (used to lessen your body’s defenses). Quinidine and diltiazem (used to treat abnormal heart rhythms). Beta blockers and verapamil (used to treat high blood pressure). Morphine and other opioids (used to treat severe pain). Ingredients The active substance is Ticagrelor.