Predo 25 mg 30 Tablets

Description

Predo belong to a group of medicines called steroids. Their full name is corticosteroids. These corticosteroids occur naturally in the body, and help to maintain health and well-being. Boosting your body with extra corticosteroids (such as Predo) is an effective way to treat various illnesses involving inflammation in the body. Predo reduce this inflammation, which could otherwise go on making your condition worse. You must take this medicine regularly to get maximum benefit from it. Predo is used in a wide range of inflammatory and auto-immune conditions including: Allergies, including severe allergic reactions Inflammation affecting the: - Lungs, including asthma - Blood vessels and heart - Bowel or kidneys - Muscles and joints, including rheumatoid arthritis - Eye or nervous system Skin conditions Some infections Some cancers, including leukaemia, lymphoma and myeloma To prevent organ rejection after a transplant. Also: To boost steroid levels when the body is not making enough natural steroid on its own To treat high calcium levels. How to use Predo should be taken following a meal to reduce the risk of gastric irritation. Different illnesses require different doses of Predo. Depending on your illness your daily dose may be between 5 and 60 mg. In some cases you may be instructed to take it every other day. Your doctor will decide when and how to treat you with Predo. Once your condition starts to get better, your doctor may change your dosage to a lower one. Your doctor may also reduce your dosage before stopping treatment completely. This may depend on your illness, your dosage and how long you have been taking this medicine. In all cases you should be careful to follow any changes. Treatment of the elderly When steroids are taken by elderly patients some of the unwanted side effects can be more serious especially brittle bone disease, diabetes, high blood pressure, infections and thinning of the skin. Use in children and adolescents The use of steroids can slow down normal growth of children and adolescents. In order to lessen this effect the tablets are often taken in a single dose every other day. Warnings and precautions Do not take Predo if you: Are allergic to prednisolone or any of the other ingredients of this medicine. Have a fungal infection Have recently had any ‘live’ vaccinations. Warnings and precautions Talk to your doctor or pharmacist before taking Predo if you have: An infection or get an infection while being treated with prednisolone Underactive thyroid gland (hypothyroidism) Liver disease or kidney failure or have had seizures Myasthenia gravis (a disease that causes muscle weakness) Tuberculosis or have ever been treated for tuberculosis Gastric ulcer, duodenal ulcer or inflammatory bowel disease (e.g. ulcerative colitis or diverticulitis) Diabetes Heart disease, e.g. heart failure or high blood pressure Had blood clots in the past (e.g. vein thrombosis) or have blood clots Mood swings or psychotic tendencies Any drug allergy Osteoporosis Adrenal tumour (phaeochromocytoma) New surgically created blood vessels or intestinal connections Scleroderma (also called systemic sclerosis, an autoimmune disease) as daily doses of 15 mg or more can increase the risk of a serious complication called acute kidney crisis. Signs of acute kidney crisis include high blood pressure and decreased urine output. Your doctor may advise you to check your blood pressure and urine levels regularly. Side Effects Common (may affect up to 1 in 10 people): Infections, the immunosuppressive effect of prednisolone may also cause infections to flare up again (eg tuberculosis) Lower concentration of certain hormones, cushings like appearance, growth retardation in children Low levels of potassium, build-up of sodium in the body, increased sugar in the blood and urine, osteoporosis Swelling due to fluid accumulation, high blood pressure Thinner skin, impaired wound healing Muscle wasting. Uncommon (may affect up to 1 in 100 people): Mental disorders (at high doses) Cataracts, glaucoma. Storage Information Store below 30°C. Store in the original package in order to protect from light. Drug Interactions It is especially important to tell your doctor if you are taking any of the following medicines: Rifampicin, isoniazid (to treat tuberculosis) Blood thinners Carbamazepine, phenobarbital, phenytoin (antiepilepsy drug) Anticholinergics (e.g. medicines for Parkinson’s disease or asthma) Cholinesterase inhibitors (for myasthenia gravis or Alzheimer’s disease) Insulin or diabetes drugs in the form of tablets. Cortisone preparations can impair the blood sugar lowering effect of diabetes drugs Cobicistat (for HIV infection) Oestrogens (e.g. birth control pills) Acetylsalicylic acid or other non-steroidal anti-inflammatory agents (NSAIDs) (used to treat pain and inflammation). The risk of peptic ulcer may increase when combined with cortisone preparations Thiazides, furosemide, ethacrynic acid (potassium lowering diuretics) Xanthines (e.g. theophylline, for treating asthma) Beta-2 stimulants (e.g. salbutamol, terbutaline, salmeterol, formoterol, for treating asthma) Amphotericin B (antibiotic for fungal infection). Ingredients The active substance is prednisolone. The other ingredients are lactose, pregelatinized starch, maize starch, microcrystalline cellulose, povidone and magnesium stearate. Specifications Predo 25 mg Tablets are white round-shaped biconvex tablets imprinted with “JPI” on one side and “61” on the other side in clear PVC/PVDC-aluminum blisters.