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Vitamin D is found in the diet and is also produced in the skin after exposure to the sun. Often vitamin D is given in combination with calcium. Prima D3™ is recommended for use when you have a normal intake of dietary calcium. Prima D3™ may be prescribed by your doctor to treat vitamin D deficiency. Deficiency of vitamin D may occur when your diet or lifestyle does not provide you enough vitamin D or when your body requires more vitamin D (for instance when you are pregnant). Prima D3™ may also be prescribed for certain bone conditions, such as thinning of the bone (osteoporosis) when it will be given to you with other medicines. How to use Important: Your doctor will choose the dose that is right for you. Normally take one Softgel capsule daily with food for treatment of Vitamin D deficiency. Warnings and precautions You are allergic to vitamin D or any of other ingredients in the capsules. You have high levels of calcium in your blood. You already have high levels of Vitamin D in your blood, or if you are especially sensitive to Vitamin D. You have kidney problems. You have an accumulation of calcium salts in the body's tissue. This product contains Soybean oil. If you are allergic to soya, do not use this product. Take special care with Prima D3™: Vitamin D should be used with caution in patients who may have increased sensitivity to its effects, and in patients with renal impairment or calculi, or heart disease, who might be at increased risk of organ damage if hypercalcemia occurred. Plasma phosphate concentrations should be controlled during vitamin D therapy to reduce the risk of ectopic calcification. It is advised that patients receiving pharmacological doses of vitamin D should have their plasma calcium concentration monitored at regular intervals, especially initially or if symptoms suggest toxicity, and in infants if they are breast-fed by mothers receiving pharmacological doses of vitamin D. Side Effects Like all medicines, this medicine can cause side effects, although not everybody gets them. Uncommon : Too much calcium in your blood (hypercalcaemia) Too much calcium in your urine (hypercalciuria). Rare : Skin rash Itching Hives Not known ( not know how often these happen): Altered bowel movements Wind Feeling sick (nausea) Stomach pain. Storage Information Do not store above 30 °C. Protect from heat and moisture. Do not freeze. Drug Interactions Thiazide diuretics, calcium or phosphate: Increased risk of hypercalcemia. Plasma calcium concentrations should be monitored. Some antiepileptics (e.g., carbamazepine, Phenobarbital, phenytoin, and primidone): Increased vitamin D requirements. Rifampicin and isoniazide: May reduce the effectiveness of vitamin D. Corticosteroids: May counteract the effect of vitamin D. Ingredients Each softgel capsule contains the active substance: Vitamin D3 (Cholecalciferol) The other ingredients are: Soybean oil, Gelatin, Glycerol, Quinoline Yellow, Brilliant Blue and Purified Water. Specifications Prima D3™ 2000 IU capsules are green transparent, oval shaped soft gelatin capsules filled with pale yellow liquid.