Trezol 2.5mg 30 Tab

Description

Trezol contains an active substance called letrozole. It belongs to a group of medicines called aromatase inhibitors. It is a hormonal (or “endocrine”) breast cancer treatment. Growth of breast cancer is frequently stimulated by oestrogens which are female sex hormones. Trezol reduces the amount of oestrogen by blocking an enzyme (“aromatase”) involved in the production of oestrogens and therefore may block the growth of breast cancer that needs oestrogens to grow. As a consequence tumour cells slow or stop growing and/or spreading to other parts of the body. Trezol is used to treat breast cancer in women who have gone through menopause i.e cessation of periods. It is used to prevent cancer from happening again. It can be used as first treatment before breast cancer surgery in case immediate surgery is not suitable or it can be used as first treatment after breast cancer surgery or following five years treatment with tamoxifen. Trezol is also used to prevent breast tumour spreading to other parts of the body in patients with advanced breast cancer. How to use The usual dose is one tablet of Trezol to be taken once a day. Taking Trezol at the same time each day will help you remember when to take your tablet. The tablet can be taken with or without food and should be swallowed whole with a glass of water or another liquid. How long to take Trezol Continue taking Trezol every day for as long as your doctor tells you. You may need to take it for months or even years. If you have any questions about how long to keep taking Trezol, talk to your doctor. Warnings and precautions Do not take Trezol If you are allergic to letrozole or to any of the other ingredients of this medicine (listed in section 6), If you still have periods, i.e. if you have not yet gone through the menopause, If you are pregnant, If you are breast-feeding. If any of these conditions apply to you, do not take this medicine and talk to your doctor. Warnings and precautions Talk to your doctor or pharmacist before taking Trezol If you have a severe kidney disease, If you have a severe liver disease, If you have a history of osteoporosis or bone fractures (see also “Follow-up during Trezol treatment” in section 3). If any of these conditions apply to you, tell your doctor. Your doctor will take this into account during your treatment with Trezol. Side Effects Most of the side effects are mild to moderate and will generally disappear after a few days to a few weeks of treatment. Some of these side effects, such as hot flushes, hair loss or vaginal bleeding, may be due to the lack of oestrogens in your body. Do not be alarmed by this list of possible side effects. You may not experience any of them. Some side effects could be serious: Uncommon (may affect up to 1 in 100 people): Weakness, paralysis or loss of feeling in any part of the body (particularly arm or leg), loss of coordination, nausea, or difficulty speaking or breathing (sign of a brain disorder, e.g. stroke). Sudden oppressive chest pain (sign of a heart disorder). Swelling and redness along a vein which is extremely tender and possibly painful when touched. Severe fever, chills or mouth ulcers due to infections (lack of white blood cells). Severe persistent blurred vision. Rare (may affect up to 1 in 1,000 people): Difficulty breathing, chest pain, fainting, rapid heart rate, bluish skin discoloration, or sudden arm, leg or foot pain (signs that a blood clot may have formed). If any of the above occurs, tell your doctor straight away. Some side effects are very common (may affect more than 1 in 10 people): Hot flushes Increased level of cholesterol (hypercholesterolaemia) Fatigue Increased sweating Pain in bones and joints (arthralgia) If any of these affects you severely, tell your doctor. Storage Information Do not store above 30ºC. Store in the original package in order to protect from moisture. Drug Interactions Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription. Ingredients The active substance is letrozole.