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Vdia contains an active substance called, vildagliptin, belongs to a group of medicines called “oral antidiabetics”. Vdia used to treat adult patients with type 2 diabetes. It is used when diabetes cannot be controlled by diet and exercise alone. It helps to control the level of sugar in the blood. Your doctor will prescribe Vdia either alone or together with certain other antidiabetic medicines which you will already be taking, if these have not proved sufficiently effective to control diabetes. Type 2 diabetes develops if the body does not make enough insulin or if the insulin that the body makes does not work as well as it should. It can also develop if the body produces too much glucagon. Insulin is a substance which helps to lower the level of sugar in the blood, especially after meals. Glucagon is a substance which triggers the production of sugar by the liver, causing the blood sugar level to rise. The pancreas makes both of these substances. How to use How much to take and when The amount of Vdia people have to take varies depending on their condition. Your doctor will tell you exactly how many tablets of Vdia to take. The maximum daily dose is 100 mg. The usual dose of Vdia is either: 50 mg daily taken as one dose in the morning if you are taking Vdia with another medicine called a sulphonylurea. 100 mg daily taken as 50 mg in the morning and 50 mg in the evening if you are taking Vdia alone, with another medicine called metformin or a glitazone, with a combination of metformin and a sulphonylurea, or with insulin. 50 mg daily in the morning if you have moderate or severe kidney disease or if you are on dialysis. How to take Vdia Swallow the tablets whole with some water. Warnings and precautions Do not use Vdia: If you are allergic to Vildagliptin or any of the other ingredients of this medicine (listed in section 6). Warnings and precautions Talk to your doctor, pharmacist or nurse before taking Vdia: If you have type 1 diabetes (i.e. your body does not produce insulin) or if you have a condition called diabetic ketoacidosis. If you are taking an anti-diabetic medicine known as a sulphonylurea (your doctor may want to reduce your dose of the sulphonylurea when you take it together with Vdia in order to avoid low blood glucose [hypoglycaemia]). If you have moderate or severe kidney disease (you will need to take a lower dose of Vdia). If you are on dialysis. If you have liver disease. If you suffer from heart failure. If you have or have had a disease of the pancreas. Side Effects Some symptoms need immediate medical attention: You should stop taking Vdia and see your doctor immediately if you experience the following side effects: Angioedema (rare: may affect up to 1 in 1,000 people): Symptoms include swollen face, tongue or throat, difficulty swallowing, difficulties breathing, sudden onset rash or hives, which may indicate a reaction called “angioedema”. Liver disease (hepatitis) (rare): Symptoms include yellow skin and eyes, nausea, loss of appetite or dark-coloured urine, which may indicate liver disease (hepatitis). Inflammation of the pancreas (pancreatitis) (frequency not known): Symptoms include severe and persistent pain in the abdomen (stomach area), which might reach through to your back, as well as nausea and vomiting. Other side effects Some patients have had the following side effects while taking Vdia and metformin: Common (may affect up to 1 in 10 people): Trembling, headache, dizziness, nausea, low blood glucose. Uncommon (may affect up to 1 in 100 people): Tiredness. Storage Information Store in the original package in order to protect from moisture. store below 30°C. Drug Interactions Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines. Your doctor may wish to alter your dose of Vdia if you are taking other medicines such as: Thiazides or other diuretics (also called water tablets) Corticosteroids (generally used to treat inflammation) Thyroid medicines Certain medicines affecting the nervous system. Ingredients The active substance is Vildagliptin.
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