Product
Product
43.70
Treatment of men with erectile dysfunction, which is the inability to achieve or maintain a penile erection sufficient for satisfactory sexual performance. In order for VIRECTA to be effective, sexual stimulation is required. Sildenafil is an oral therapy for erectile dysfunction. In the natural setting, i.e. with sexual stimulation, it restores impaired erectile function by increasing blood flow to the penis. How to use Use in adults: The recommended dose is 50 mg taken as needed approximately one hour before sexual activity. Based on efficacy and tolerability, the dose may be increased to 100 mg or decreased to 25 mg. The maximum recommended dose is 100 mg. The maximum recommended dosing frequency is once per day. If VIRECTA is taken with food, the onset of activity may be delayed compared to the fasted state. Use in Elderly: Dosage adjustments are not required in elderly patients. Use in Patients with impaired renal function: The dosing recommendations described in “Use in adults” apply to patients with mild to moderate renal impairment (creatinine clearance = 30-80 mL/min). Since sildenafil clearance is reduced in patients with severe renal impairment (creatinine clearance < 30 mL/min) a 25 mg dose should be considered. Based on efficacy and tolerability, the dose may be increased to 50 mg and 100 mg. Use in Patients with impaired hepatic function: Since sildenafil clearance is reduced in patients with hepatic impairment (e.g. cirrhosis) a 25 mg dose should be considered. Based on efficacy and tolerability, the dose may be increased to 50 mg and100 mg. Use in Children: VIRECTA is not indicated for individuals below 18 years of age. there is no relevant indication for use in children. Warnings and precautions Do not use VIRECTA if: You are allergic (hypersensitive) to Sildenafil Citarte or any of the other ingredients listed in Section 6. If you are not sure, talk to your doctor or pharmacist before using VIRECTA. The contraindications of VIRECTA: Hypersensitivity to the active substance or to any of the excipients. Consistent with its known effects on the nitric oxide/cyclic guanosine monophosphate (cGMP) pathway, sildenafil was shown to potentiate the hypotensive effects of nitrates, and its coadministration with nitric oxide donors (such as amyl nitrite) or nitrates in any form is therefore contraindicated. Agents for the treatment of erectile dysfunction, including sildenafil, should not be used in men for whom sexual activity is inadvisable (e.g. patients with severe cardiovascular disorders such as unstable angina or severe cardiac failure). VIRECTA is contraindicated in patients who have loss of vision in one eye because of non-arteritic anterior ischaemic optic neuropathy (NAION), regardless of whether this episode was in connection or not with previous PDE5 inhibitor exposure. The safety of sildenafil has not been studied in the following sub-groups of patients and its use is therefore contraindicated: severe hepatic impairment, hypotension (blood pressure < 90/50 mmHg), recent history of stroke or myocardial infarction and known hereditary degenerative retinal disorders such as retinitis pigmentosa (a minority of these patients have genetic disorders of retinal phosphodiesterases). The special warnings and precautions for use: A medical history and physical examination should be undertaken to diagnose erectile dysfunction and determine potential underlying causes, before pharmacological treatment is considered. Prior to initiating any treatment for erectile dysfunction, physicians should consider the cardiovascular status of their patients, since there is a degree of cardiac risk associated with sexual activity. Sildenafil has vasodilator properties, resulting in mild and transient decreases in blood pressure. Prior to prescribing sildenafil, physicians should carefully consider whether their patients with certain underlying conditions could be adversely affected by such vasodilatory effects, especially in combination with sexual activity. Patients with increased susceptibility to vasodilators include those with left ventricular outflow obstruction (e.g., aortic stenosis, hypertrophic obstructive cardiomyopathy), or those with the rare syndrome of multiple system atrophy manifesting as severely impaired autonomic control of blood pressure.VIRECTA potentiates the hypotensive effect of nitrates. Side Effects Nervous system disorders Very common: Headache. Common: Dizziness. Eye disorders Common: Altered vision (increased perception of light, blurred vision). Common: Chromatopsia (mild and transient, predominantly colour tinge to vision). Cardiac disorders Common: Palpitations. Vascular disorders Very common:Flushing. Respiratory, thoracic and mediastinal disorders. Common:Nasal congestion. Gastrointestinal disorders Common:Dyspepsia. Storage Information Store below 30°C. Store in the original package, in order to protect from moisture. Drug Interactions Interaction with nitrate medications: It should not be used with medications containing nitrates (such as heart medications), as this can lead to a severe drop in blood pressure. Ingredients The active substance is Sildenafil Citrate. Specifications Clear PVC/Aluminium blisters in cartons of 4 tablets.