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Zyrosa belongs to a group of medicines called statins. You have been prescribed ZYROSA because: You have a high cholesterol level. This means you are at risk from a heart attack or stroke. Zyrosa is used in adults, adolescents and children 6 years or older to treat high cholesterol. You have been advised to take a statin, because changing your diet and taking more exercise were not enough to correct your cholesterol levels. You should continue with your cholesterol-lowering diet and exercise while you are taking Zyrosa. Or You have other factors that increase your risk of having a heart attack, stroke or related health problems. Heart attack, stroke and other problems can be caused by a disease called atherosclerosis. Atherosclerosis is due to build up of fatty deposits in your arteries. How to use Usual doses in adults If you are taking Zyrosa for high cholesterol: Starting dose Your treatment with Zyrosa must start with the 5 mg or the 10 mg dose, even if you have taken a higher dose of a different statin before. The choice of your start dose will depend upon: Your cholesterol level. The level of risk you have of experiencing a heart attack or stroke. Whether you have a factor that may make you more sensitive to possible side effects. Please check with your doctor or pharmacist which start dose of Zyrosa will best suit you. Your doctor may decide to give you the lowest dose (5 mg) if: You are of Asian origin (Japanese, Chinese, Filipino, Vietnamese, Korean and Indian). You are over 70 years of age. You have moderate kidney problems. You are at risk of muscle aches and pains (myopathy). Taking your tablets Swallow each tablet whole with a drink of water. Take Zyrosa once daily. You can take it at any time of the day with or without food. Try to take your tablet at the same time every day to help you to remember it. WARNINGS AND PRECAUTIONS: Talk to your doctor or pharmacist before taking Zyrosa. If you have problems with your kidneys. If you have problems with your liver. If you have had repeated or unexplained muscle aches or pains, a personal or family history of muscle problems, or a previous history of muscle problems when taking other cholesterol-lowering medicines. Tell your doctor immediately if you have unexplained muscle aches or pains especially if you feel unwell or have a fever. Also tell your doctor or pharmacist if you have a muscle weakness that is constant. If you regularly drink large amounts of alcohol. If your thyroid gland is not working properly. If you take other medicines called fibrates to lower your cholesterol. Please read this leaflet carefully, even if you have taken other medicines for high cholesterol before. If you take medicines used to treat the HIV infection e.g. ritonavir with lopinavir and/or atazanavir, please see Other medicines and Zyrosa. Side Effects Stop taking Zyrosa and seek medical help immediately if you have any of the following allergic reactions: Difficulty in breathing, with or without swelling of the face, lips, tongue and/or throat Swelling of the face, lips, tongue and/or throat, which may cause difficulty in swallowing Severe itching of the skin (with raised lumps). Common possible side effects (these may affect between 1 in 10 and 1 in 100 patients): Headache Stomach pain Constipation Feeling sick Muscle pain Feeling weak Dizziness Storage Information Store below 30ºC. Protect from light and moisture Drug Interactions Tell your doctor if you are taking any of the following: ciclosporin (used for example, after organ transplants), warfarin or clopidogrel (or any other drug used for thinning the blood), fibrates (such as gemfibrozil, fenofibrate) or any other medicine used to lower cholesterol (such as ezetimibe), indigestion remedies (used to neutralise acid in your stomach), erythromycin (an antibiotic), fusidic acid (an antibiotic – please see Warnings and precautions), an oral contraceptive (the pill), hormone replacement therapy or anti-viral medications such as ritonavir with lopinavir and/or atazanavir or simeprevir (used to treat infections, including HIV or hepatitis C infection – please see Warnings and precautions). The effects of these medicines could be changed by Zyrosa or they could change the effects of Zyrosa. Ingredients The active substance in Zyrosa is rosuvastatin. Specifications Pink round shaped film coated tablet, debossed with “R 20” on one side and plain on other side.
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