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Sapofen Tablets belongs to a group of medicines called anti-inflammatory pain killers. They can be used to relieve pain and inflammation in conditions such as osteoarthritis, rheumatoid arthritis (including juvenile rheumatoid arthritis or Still’s disease), arthritis of the spine, ankylosing spondylitis, swollen joints, frozen shoulder, bursitis, tendinitis, tenosynovitis, lower back pain, sprains and strains. Sapofen Tablets can also be used to treat other painful conditions such as toothache, pain after operations, period pain and headache, including migraine. It can also be used to reduce fever and relieve the symptoms of colds and flu. How to use Take your Sapofen Tablets with or after food, with a glass of water. Sapofen Tablets should be swallowed whole and not chewed, broken, crushed or sucked to help prevent discomfort in the mouth or irritation in the throat. DOSAGE: Adults and children over 12 years The usual dosage is 600 to 1800 mg spread throughout the day. Your doctor may choose to increase this depending on what you are being treated for; but no more than 2400 mg should be taken in one day. Children The usual daily dose is 20 mg per kg of bodyweight each day, given in divided doses. Sapofen Tablets should NOT be taken by children weighing less than 7 kg. The 600 mg tablets should not be given to children under the age of 12 years. In cases of severe juvenile arthritis your doctor my increase the dosage up to 40 mg/kg in divided doses. Warnings and precautions If the answer to any of the following questions is ‘YES’ please tell your doctor or pharmacist BEFORE taking any Sapofen Tablets: Are you pregnant or planning to become pregnant, or are you breast-feeding? Sapofen tablets may make it more difficult to become pregnant. You should inform your doctor if you are planning to become pregnant or if you have problems becoming pregnant. Are you sensitive (allergic) to any of the ingredients in the tablets? Do you have, or have you previously had, a stomach ulcer or other gastric complaint? Do not take Sapofen Tablets if you currently have a peptic ulcer (ulcer in your stomach or duodenum) or bleeding in your stomach, or have had two or more episodes of peptic ulcers, stomach bleeding or perforation in the past. Do you have a condition which increases your tendency to bleeding? Do you suffer from asthma or have you ever had an allergic reaction or suffered from wheezing after taking ibuprofen, aspirin or other anti-inflammatory pain killers? Do you suffer from swelling and irritation inside the nose? Do you suffer from liver or kidney disease? Do you suffer from heart disease? Medicines such as Sapofen Tablets may be associated with a small increased risk of heart attack (myocardial infarction) or stroke. Any risk is more likely with high doses and prolonged treatment. Do not exceed the recommended dose or duration of treatment. You should discuss your treatment with your doctor or pharmacist before taking Sapofen Tablets if you: Have heart problems including heart failure, angina (chest pain) or you have had a heart attack, bypass surgery or peripheral artery disease (poor circulation in the legs or feet due to narrow or blocked arteries). Have any kind of stroke or think that you might be at risk of these conditions (e.g., if you have a family history of heart disease or stroke, high blood pressure, diabetes, high cholesterol or are a smoker). Do you have systemic lupus erythematosus (SLE, sometimes known as lupus) or a connective tissue disease (autoimmune diseases affecting connective tissue)? Do you have chicken pox or shingles? Are you or your child dehydrated? As there is a risk of kidney damage in dehydrated children, adolescents and the elderly. Side Effects STOP TAKING Sapofen Tablets and seek immediate medical help if you experience: Signs of aseptic meningitis such as severe headache, high temperature, stiffness of the neck or intolerance to bright light. Signs of intestinal bleeding such as Passing blood in your faeces (stools/motions) Passing black tarry stools Vomiting any blood or dark particles that look like coffee grounds Other side effects Common (affects up to 1 in 10 people): Feeling dizzy or tired Diarrhoea, wind, constipation Headache Storage Information Store below 30°C. Drug Interactions In particular you should tell your doctor or pharmacist if you are taking any of the following medicines in addition to those mentioned above: Diuretics (water tablets) Cardiac glycosides, such as digoxin, used to treat heart conditions Lithium Zidovudine (an anti-viral drug) Steroids (used in the treatment of inflammatory conditions) Methotrexate (used to treat certain cancers and rheumatoid arthritis) Medicines known as immunosuppressants such as ciclosporin and tacrolimus (used to dampen down your immune response) Medicines known as selective serotonin reuptake inhibitors (ssris), used for the treatment of depression Antibiotics called quinolones such as ciprofloxacin Aminoglycosides (a type of antibiotic) Mifepristone Any other ibuprofen, such as those you can buy without a prescription Ingredients The active ingredient in Sapofen Tablets is ibuprofen Core:Hydroxypropyl Cellulose, Colloidal Silicon Dioxide, Avicel PH 101, Sodium Lauryl Sulphate, Croscarmellose Sodium Type A, Avicel PH 102, Magnesium stearate, Purified Talc. Coating Material: Opadry OY-L-33025 Dark Orange and Purified Water.
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